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Paychex HR and Payroll Services in Missouri

Missouri businesses are looking for results, not promises. That’s why companies in Missouri and nationwide choose Paychex for their payroll and HR needs.

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Paychex Services for Missouri Businesses

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Find the Right Payroll Services

As part of our payroll offerings, you'll get instant access to our payroll tax service, Taxpay®, for automated tax administration.

Paychex Flex payroll overview video
Payroll Overview
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Help Cover Employees’ Medical Expenses and Lost Pay

Paychex Insurance Agency can help you find the right coverage for your business and help stabilize your business cash flow with our Workers’ Compensation Payment Service.

An employee applying for workers' comp

Our All-in-One PEO Helps You Manage HR, Payroll, and Benefits

Get help attracting and keep employees, offer world-class benefits, simplify payroll, and more, with our all-in-one HR solution.

A busy office with employee working together
What Is a PEO
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Liability Insurance To Help Protect Your Business

Whether your business is solely online, brick-and-mortar, or a combination of both — and no matter what your size — Paychex Insurance Agency can help you find the right business insurance policies.

business owner reviewing their Business Insurance Service

Paychex Flex®: The Single Platform for your HR, Payroll and Benefits

Paychex Flex is our all-in-one HR technology platform. It automates payroll processing for companies like yours while integrating your employee data with HR and benefits for easier management.

Convenient Service

  • Paychex Flex includes more than 30 self-service actions for increased employee convenience and independence
  • Reach us through chat or over the phone — we work with you the way you want to work
  • Get up-to-date information on regulations for businesses like yours
Employee support column

Contact a Paychex Payroll and HR Professional

Our highly trained, experienced customer service specialists can answer your important questions on HR, payroll, and benefits when you need it. That means 24/7.  We use industry expertise, innovative thinking, and extensive customer support to work with you the way you want to work.

hr and payroll customer service representative

Find the Right Solution for Your Business

Paychex has the technology, expertise, and customer service that can help move your business forward. We’ll help you find the right solution that works best for your individual needs, no matter the size of your business.

Find Your Solution
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Paychex Is the Smart Choice for Payroll and HR Services in Missouri

  • Named one of the World’s Most Ethical Companies® by Ethisphere® — a 15-time honoree
  • We’ll help you recruit employees and simplify onboarding
  • Work with top-tier national/regional health, dental and vision carriers
  • Get quick, easy, on-the-go HR, payroll, and benefits solutions
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Additional Resources for Businesses in Missouri

Payroll Solutions for Businesses of Every Size

Paychex Payroll Services can save you and your business time so that you can focus on what matters most. Hear from our customers about why they choose Paychex to help ease the payroll burden.

"StratasCorp Technologies was quickly outgrowing their payroll provider. Paychex helped them save 10 hours a month and $10,000 a year in tax penalties".

“What we learned in a discovery process with Paychex was all the different services that were available. That was music to my ears as a new CFO …. From an efficiency standpoint, knowing we could have our 401(k) under your program, having the management and compliance done with one party obviously makes my life a lot easier.”

"As a recruitment tool, the 401(k) is a very integral part of what we offer our employees."

"The daily time that I don’t spend on (payroll) … it really changes my daily routine. It allows me to make phone calls, answer emails, talk with general contractors and talk with my franchise (personnel). Having the ability to do that streamlines both processes."

Plumbing Doctor was spending too much time tracking down information on how new regulations could impact their business and doing research to get answers for their HR questions. Working with Paychex PEO provides them with 80 hours a month to focus on growing their business.

Recognized by Industry Experts for Our Innovation, Ethics, and Performance

World's Most Ethical Companies Award 2024
World’s Most Ethical Companies
Customer Satisfaction - IDC SaaS Award
Leader in Customer Satisfaction
FORTUNE World's Most Innovative Companies Award
America’s Most Innovative Companies
Best Small Business-focused solution from HR Tech 2024 award
Best Small Business-Focused Solution
PLANSPONSOR Largest 401(k) Recordkeeper by Number of Plans
Largest 401(k) Recordkeeper
Apex training award winner 2024
World’s Top Training Organizations

Join Our 745,000+ Customers and Get Help Managing HR, Payroll, and Benefits for Your Missouri Business